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WHEATON

800.225.1437 (U.S. & Canada Only) | 856.825.1100 | 856.825.1368 (F) |

www.wheaton.com

Gray Bromobutyl / 39 with Complete Coat

Pros:

Low gas and vapor permeablilty, good for multiple piercing applications,

compatible with most cephalosporin's, resistant to animal, vegetable, and mineral oils,

good resistance to aliphatic, aromatic and chlorinated solvents

Cons:

Not recommended for use with ketones.

A, B, C

Gray Bromobutyl / 46

Pros:

Low gas and vapor permeability, good for multiple piercing applications, excellent

moisture absorption and desorption properties following autoclave and lyophilization

drying cycles.

Cons:

Poor resistance to mineral oil, aliphatic, aromatic, and chlorinated solvents. Can

be autoclaved and irradiated.

Gray Bromobutyl / 47

Pros:

Low gas and vapor permeability, great for multiple piercing applications

after gamma irradiation, ultra low extractable compound, compatible with most

cephalosporin’s, very good moisture absorption and desorption properties following

autoclave and lyophilization drying cycles, compatible with WFI applications.

Cons:

Poor resistance to mineral oil, aliphatic, aromatic, and chlorinated solvents. Can

be autoclaved and irradiated.

Gray Bromobutyl / 50

Pros:

Low gas and vapor permeability, very good properties regarding ozone, animal

and vegetable oil.

Cons:

Not good for multiple piercing applications, poor resistance to mineral oil, aliphatic,

aromatic, and chlorinated solvents. Can be autoclaved.

Gray Chlorobutyl / 45

Pros:

Low gas and vapor permeability, good for multiple piercing applications, resistant

to animal and vegetable oils.

Cons:

Poor resistance to mineral oil, aliphatic, aromatic, and chlorinated solvents. Can

be autoclaved and irradiated.

Gray Chlorobutyl / 46

Pros:

Low gas and vapor permeability, good for multiple piercing applications, resistant

to animal and vegetable oils, good for lyophilization applications.

Cons:

Poor resistance to mineral oil, aliphatic, aromatic, and chlorinated solvents. Can

be autoclaved and irradiated.

Gray Chlorobutyl / 50

Pros:

Low gas and vapor permeability, resistant to animal and vegetable oil, good for

lyophilization applications.

Cons:

Poor resistance to mineral oil, aliphatic, aromatic, and chlorinated solvents. Can

be autoclaved and irradiated.

Gray Chlorobutyl / 55

Pros:

Low gas and vapor permeability, resistant to animal and vegetable oil, good for

lyophilization applications.

Cons:

Not good for multiple piercing applications, poor resistance to mineral oil, aliphatic,

aromatic, and chlorinated solvents. Can be autoclaved and irradiated

Gray Chlorobutyl / Isoprene Blend / 40 with FEP Facing

Pros:

Barrier properties of FEP, good coring characteristics, fair resistance to gas and

moisture transmission compared to red isoprene.

Cons:

Contains dry natural rubber. Can be autoclaved.

Gray Chlorbutyl / Isoprene Blend / 50

Pros:

Good coring and reseal characteristics, fair resistance to gas and moisture

transmission compared to red isoprene, good for lyophilization applications.

Cons:

Contains dry natural rubber. Can be autoclaved.

Black Halobutyl / 60

Pros:

Good resistance to gas and vapor transmission, good for lyophilization applications.

Cons:

Poor coring and reseal characteristics, not good for use with acidic products. Can

be autoclaved.

Red Natural / 40

Pros:

Good coring and reseal characteristics.

Cons:

Contains dry natural rubber, poor gas and vapor transmission compared to butyl,

not appropriate for products that require an inert gas blanket, not good for use with

acidic products or solvents. Can be autoclaved and irradiated.

Natural Silicone / 55

Pros:

Good for high heat applications, can withstand multiple steam autoclaves.

Cons:

Very poor barrier to gas and vapor transmission, not appropriate for products that

require an inert gas blanket. Can be autoclaved and irradiated.

Black FKM / 55

Pros:

Low gas and vapor permeability, resistant to animal, vegetable and mineral oil,

aliphatic, aromatic, and chlorinated solvents, good for high heat applications.

Cons:

Not recommended for ketones. Can be autoclaved.

Black EPDM

Pros:

Excellent water and chemical resistance, good resistance to gas permeation, good

for high heat applications.

Cons:

Poor oil resistance, poor resistance to solvents. Can be autoclaved.

2-Leg Lyophilization Stoppers

3-Leg Lyophilization Stoppers

Rubber Stopper Formulation Descriptions

Listed below are the primary stopper formulations with general descriptions that are supplied by WHEATON.

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Technical Data, Closures